Introduction: Biochemistry and Molecular Biology 8010

Table of Contents

{1} COURSE GOALS AND PHILOSOPHY

{2} Course goals...

{3} Goals...

{4} Goals...

{5} Hope is that...

{6} First Part of Course

{7} A direct consequence of all of this is...

{8} Both phototrophs and chemotrophs (figure 1.2)...

{9} Energy conservation by making ATP

{10} NAD+ and NADP+ receive reducing equivalents

{11} Flavin mononucleotide, FMNFlavin adenine dinucleotide, FAD

{12} Only with the phototrophs is the net chemistry reversed...

{13} The photoactive pigments of photosynthesis are tetrapyrrole/Mg+2 complexes

{14} Biochemistry is... Organized structures

{15} A zebra fish supports the book’s view..

{16} Biochemistry is...

{17} Goodsell (1993) uses outlines of shapes

{18} Goodsell (1993)...

{19} However, even accurate representation misleads, because...

{20} Molecules...

{21} 65 picoseconds of movement

{22} On the microsecond time scale,...

{23} Some of these collisions last a while

{24} Sometimes the complex formed is chemically competent...

{25} Molecules...

{26} Molecules...

{27} Molecules...

{28} Sticky molecules...

{29} Sticky molecules...

{30} Non-bonding interactions …

{31} The hydrophobic effect...

{32} Biochemistry is...

{33} Two key concepts of biological selectivity

{34} Biochemistry is...

{35} Key then is enzymes and how they work...

{36} Enzymes function...

{37} R. V. Eck's "Enzymes Are MOLECULAR Machines"

Email: wampler@bchiris.bmb.uga.edu

Course Page: http://bmbiris.bmb.uga.edu/wampler/8010

Assignments:

Chapter 1 of Garrett and Grisham

References and Further Reading

Biology On-Line Site

D. S. Goodsell (1991), Inside a Living Cell. Trends Biochem. Sci. 16, 203-206.

D. S. Goodsell (1993), "The Machinery of Life" Springer-Verlag, New York.

D. S. Goodsell (1996), "Our Molecular Nature: The Body's Motors, Machines and Messages" Springer-Verlag, New York.

T. Hager (1995), Force of Nature: The Life of Linus Pauling, Simon and Schuster, New York.

Kimball's Biology Pages

M. W. King, Introduction to Vitamins, at Terre Haute Center for Medical Education, Indiana State University

D. J. Plummer (1996), Responses of Acer pseudoplatanus cell suspension cultures to elicitation with chitosan and cell wall fragments from yeast extract (Saccharomyces cerevisiae)masters thesis, University of Georgia, Athens, GA