Maude Menten, one of the first women doctors in Canada and later a pathologist at the University of Chicago, worked with Leonor Michaelis in experimental support for the kinetic model of enzyme kinetics that we know as the Michaelis-Menten equation (1913). The equation itself was formulated earlier by Victor Henri (1903) based on poorly controlled experiments on the action of invertase. The discovery of pH (1909) made it possible for Michaelis and Menten to buffer their reactions, carrying them out under more controlled conditions than had been previously done by Henri and others.

For more on the life and work of this early woman biochemist see the Women in Science site a the University of Toronto.