PROTEIN AND PEPTIDE STRUCTURE:
AMINO ACIDS, STRUCTURES & PROPERTIES

Table of Contents

{1} PROTEIN AND PEPTIDE STRUCTURE*

{2} The assymetric center at C?...

{3} Note about,

{4} PEPTIDE =

{5} PROTEINS =

{6} Amino Acids:

{7} Amino acids...

{8} There has always been...

{9} However,...

{10} Chemical classifications can mislead.

{11} Some ideas from these data.

{12} Some ideas from these data...

{13} One more genetically encoded...

{14} Other amino acids in proteins

{15} Other amino acids are found...

{16} Amino acids are amphoteric.

{17} Chemical modifications

{18} Thiol (cysteine -S-H):

{19} Thiols cont.:

{20} Amino group reactions:

{21} Amino reactions cont….

{22} Amino reactions cont….

{23} Reactions of other sidechains:

{24} Remember, reactions conditions can modulate results

{25} Cross-Linking Reagents:

{26} Hetero-bifunctional cross linkers:

{27} More specificity can be

{28} Detection of amino-acids and proteins

{29} UV-visible absorption of aromatics & cystine

Email: wampler@bchiris.bmb.uga.edu

Home Page: http://bmbiris.bmb.uga.edu/wampler/8010

Assignment:

CHAPTER 4 of Garrett & Grisham

David E. Metzler (1977), Biochemistry, Academic Press, Inc., N. Y.

Web Page on Amino acid optical isomers

Web Page on Amino acid properties

The Handbook of Biochemistry, Chemical Rubber Company.

Richard P. Haugland (1996) Handbook of Fluorescent Probes and Research Chemicals, Molecular Probes Inc., Eugene, OR.

Dayhoff, Swartz & Orcutt, Atlas of Protein Sequence and Structure, Vol. 5, Supplement 3 (1978)