Tuesday lectures in italics
Thurday lectures in BOLD
(W) lecturer is J. E. Wampler
(M) Lecturer is Kelley Moremen
August 2000 S M Tu W Th F S 1 2 3 4 5
6 7 8 9 10 11 12
13 14 15 16 17 18 19 Classes Start:Intro to Biochemistry, Enzymology & Protein Structure(W)
20 21 22 23 24 25 26 Water properties, Acids & Bases and pH; Intro to Thermodynamics(W) Proteins, Peptids & Amino Acids(W) 27 28 29 30 31 What the PDB teaches us?; Folding is limited in practice (W) Introduction to Structural Motifs(W) September 2000 S M Tu W Th F S 1 2
3 4 5 6 7 8 9 Motifs, Motifs, Motifs...(W);Protein purification and analysis(W) & 1ST QUIZ The Complete Description(W) 10 11 12 13 14 15 16 From Protein Science to Enzymology & Thermodynamics of Enzyme Reactions (W) Transistion State Theory (W) 17 18 19 20 21 22 23 Binding Studies; QUIZ 2 (W), Steady State Kinetics and the Michaelis Menten Equation(W) 24 25 26 27 28 29 30 Transistion State Theory (W); Cleland Nomenclature, reaction schemes and diagrams (W) October 2000 S M Tu W Th F S 1 2 3 4 5 6 7 Mutliple substrates and effectors, Defining and Analyzing Kinetic Mechanisms (W); TAKE HOME DUE Multisite enzymes, Kinetic Cooperativity and Allosteric Regulation (W) 8 9 10 11 12 13 14 Transient State Kinetics (W); MID POINT; MID TERM (W)
15 16 17 18 19 20 21 Protein Structure: motifs and domains (M), Enzyme catalytic mechanisms (M)
22 23 24 25 26 27 28 Case studies: Lysozyme and glycosidases (M), FALL BREAK
29 30 31 Case studies: Serine proteases (M)
November 1999 S M Tu W Th F S 1 2 3 4 Case studies: Nucleotide binding proteins(M)
5 6 7 8 9 10 11 Case studies: Vitamins and coenzymes (M), 4th QUIZ (M)
12 13 14 15 16 17 18 Regulation of enzyme activity: cooperativity(M), Glycolysis and gluconeogenesis (M)
19 20 21 22 23 24 25 Regulation of glycogen synthesis and breakdown, (NOTE:homework Problem set due Tuesday), Thanksgiving Break 26 27 28 29 30 Protein structure and function in signal cascades (M), Fermentation, pentose phosphate pathway, Links to energy charge (M),
December 1999 S M Tu W Th F S 1 2
3 4 5 6 7 8 9 Summary and Review, Last Day of Class
10 11 12 13 14 15 16 Final Exam (12:00 noon - 3:00 pm)
17 18 19 20 21 22 23
24 25 26 27 28 29 30
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