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Physical Biochemistry /
Bioluminescence / Fluorescence

Lee, John W. E-mail: jlee@uga.edu
The major research interest is in the biophysical aspects of bioluminescence. We utilize picosecond fluorescence dynamics and macromolecular structural methods: high-field nuclear magnetic resonance and X-ray crystallography. The properties of certain fluorescent proteins occurring in the bioluminescent bacteria have been given detailed study, such as spectral properties, primary sequence, and three-dimensional structure. Current work concentrates on the calcium-regulated photoproteins, obelin and aequorin. These studies involve collaborations with groups in Holland and Russia with support by the Office of Naval Research.
Keywords: bioluminescence, fluorescence, picosecond, bacterial luciferase, photobacterium, photoprotein, aequorin, obelin, lumazine protein, NMR, X-ray crystallography.




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